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Research Summary: Many Patients Struggle to Stop Buprenorphine Use

August 6, 2018 by ATForum

“Many patients who want to stop using buprenorphine for opioid use disorder were not able to, according to findings recently published in Drug and Alcohol Dependence.

Researchers conducted a retrospective cohort study of 1,308 adults receiving buprenorphine. During a median follow-up of 316 days, 48 patients tapered off the medication, for an estimated proportion of 15% of all patients. Only 22 of these tapers were medically supervised, and after a median follow-up of 490 days, 13 of the 48 patients resumed buprenorphine treatment.

Characteristics of the 48 patients who were able to taper off buprenorphine included: mean age of initial opioid use was 22 years; mean age of enrolling in an office-based addiction treatment clinic was 38 years; 74.5% were white; 37.5% were women; and 30.8% had not finished high school. In addition, 41.7% of the 48 patients who were able to stop using buprenorphine had a lowest mean daily dose of more than 8 mg before taper completion, 31.3% of patients had a minimum daily dose 4 mg or less prior to completing the taper, and 27.1% had a minimum dose between 8 mg and 5 mg.”

Read more at: https://www.healio.com/family-medicine/addiction/news/online/%7B09f153f5-648a-439d-bc5e-91aabd98f71a%7D/many-patients-struggle-to-stop-buprenorphine-use

Source: Healio.com – July 18, 2018

Filed Under: 2018, Medication-Assisted Treatment (MAT), News Updates

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