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Study Results: Methadone Reduces Mortality in Opioid-Dependent Patients

May 8, 2017 by ATForum

“Retention in methadone treatment is associated with a substantial reduction in the risk for all-cause and overdose mortality in patients dependent on opioids, according to a study published in the BMJ.

“Our review suggests that time spent in opioid substitution treatment with methadone is associated with an average reduction of 25 deaths/1000 person years,” the authors stated. “Findings also suggest that opioid substitution treatment with buprenorphine could be associated with a reduction in mortality, with a similar risk across all time in treatment (about 4 deaths/1000 person years) consistent with its safety profile and a risk after cessation higher in the first 4 weeks than in the remainder of time out of treatment.”

Read more at: http://www.clinicaladvisor.com/infectious-diseases-information-center/methadone-reduces-the-risk-for-opioid-mortality/article/654797/

Source: ClinicalAdvisor.com – May 3, 2017

Filed Under: 2017, Medication-Assisted Treatment (MAT), News Updates

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