Dr. Jana Burson Blog: Drug Interactions with Methadone

“Recently, medical directors of opioid treatment programs in my state pondered how to handle the risk of medication interactions with methadone. In my area of the country, chart reviews of patients who died while taking methadone revealed many decedents were taking other medications with known interactions with methadone. Obviously, we want to prevent these deaths, and need to protect against drug interactions.

To predict a possible drug interaction, the OTP doctor must know all of the other medications that the patient is taking, both prescription and non-prescription. I assume all doctors at opioid treatment programs ask the patients what medications they are prescribed on the first day, along with what they take over the counter. That’s a good start, but often it’s not sufficient.”


Source: Dr. Jana Burson – March 25, 2014

New Drug-Drug Interactions in Opioid Therapy App for iPhones, iPad and Android Devices Now Available

A new tool is available that reviews the current evidence on the likelihood of drug−drug interactions between either methadone or buprenorphine and 120 commonly prescribed drugs. It is available as a website and an app for both Apple and Android devices.

The tool was created using content from the 7th Edition of ‘Drug–Drug Interactions in Opioid Therapy edited by Elinore McCance-Katz who was recently appointed Chief Medical Officer of the Substance Abuse and Mental Health Services Administration (SAMHSA). It was also peer reviewed by the European Opiate Addiction Treatment Association (Europad).

The tool is available at www.opioiddruginteractions.com.  You can use the tool online or click on the link to download the app on the Apple App Store or Google Play Store.

Source: OpioidDrugInteractions.com – April 2013

New Webinar: Drug Interactions with Opioids: What Do We Know and What Do We Need to Know?

This June 27 webinar will provide an overview of drug interactions with opioid medications with a focus on methadone and buprenorphine. Epidemiology of opioid misuse and adverse effects, and principles of pharmacokinetics and pharmacodynamics that underlie drug interactions will be discussed as will examples of adverse drug-drug interactions.

This series of webinar presentations is being presented by the Physician Clinical Support System-Opiates, PCSS-O, sponsored by the Substance Abuse and Mental Health Service Administration and the Center for Substance abuse Treatment. This is part of a grant awarded to the American Academy of Addiction Psychiatry, American Psychiatric Association, and the American Osteopathic Academy of Addiction Medicine/


Source:  Physician Clinical Support System-Opiates

All links accessed June 21, 2012.

Site last updated July 17, 2014 @ 5:55 pm