“During 2014, the 25th anniversary of the identification of the hepatitis C virus (HCV), it became clear that a spate of new antiviral drugs and novel treatment strategies heralded a future in which a significant proportion of patients can be cured of HCV infection. The evolving saga is highlighted by efforts at enhanced early recognition, the development of better-tolerated and more effective therapeutic regimens, and the emergence of ever-changing management guidelines.
The current and highly successful strategic treatment approach is similar to that used for the treatment of HIV infection. Antiretroviral agents with different mechanisms of action are combined in order to increase efficacy and prevent resistance. However, not all eligible patients with HCV have been tested and identified, and even fewer have been referred for care or offered treatment. Thus, HCV infection remains a significant problem worldwide, with risk for progression to cirrhosis, liver failure, and hepatocellular carcinoma (HCC).
At this year’s Digestive Disease Week, investigators discussed issues related to screening efforts, the natural history of HCV infection, the safety and efficacy of the next wave of antiviral agents, access to care, and affordability of treatment.”
Read more at: http://www.medscape.com/viewarticle/846347?src=wnl_edit_specol&uac=84966BT (Free registration required).
Source: Medscape.com – June 15, 2015